ALIX Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90048-50, BS90048-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8WUM4(Human) Q9WU78(Mouse) Q9QZA2(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC FC
All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
Background: ALG-2-interacting protein (Alix), also designated programmed cell death 6-interacting protein (PDCD6-interacting protein), is a cytoplasmic protein. Alix interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. Additionally, Alix interacts with the endosomal sorting complexes required for transport (ESCRT) proteins (Tsg101 and CHMP4) and can associate with HIV-1. The endophilins (SH3P4, SH3P8 and SH3P13), enzymes that change curvature of the membrane that are required for early and late steps of coated vesicle formation, also bind to Alix. Alix is involved in the concentration and sorting of cargo proteins of the multivesicular body for incorporation into vesicles.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: ALIX polyclonal antibody detects endogenous levels of ALIX protein.
Bioworld Molecular Weight: 96 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ALIX on different cell lysates using anti-ALIX antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: PC-12
Lane 3: NIH-3T3, Immunohistochemical analysis of paraffin-embedded rat stomach tissue using anti-ALIX antibody. Counter stained with hematoxylin.
Alternative Name: PDCD6-interacting protein, PDCD6IP, AIP1, ALIX, KIAA1375, AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, Hp95, KIAA1375, MGC17003, PDC6I, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodified