ALS2CR8 Polyclonal Antibody
Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Catalogue Numbers: BS67642-50, BS67642-100
Sizes: 50µl, 100µl
Swiss-Prot: Q8N187
Host: Rabbit
Reactivity: Human
Applications: WB, IHC
Background: Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification and Purity: The antibody was purified by immunogen affinity chromatography.
Specificity: Recognizes endogenous levels of ALS2CR8 protein.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ALS2CR8 expression in THP1 (A), MCF7 (B), Hela (C) whole cell lysates., Immunohistochemical analysis of ALS2CR8 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Bioworld Molecular Weight: ~ 250 kDa
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Alternative Name: ALS2CR8; Calcium-responsive transcription factor; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; CaRF; Testis development protein NYD-SP24
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ALS2CR8. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified