Aly Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10535-50, MB10535-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q86V81
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Background: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 27 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Aly/Ref in rat brain, rat heart lysates using Aly antibody., Western blot analysis of Aly/Ref in HepG2, mouse liver lysates using Aly/Ref antibody.
Alternative Name: ALYREF; ALY; BEF; THOC4; THO complex subunit 4; Tho4; Ally of AML-1 and LEF-1; Aly/REF export factor; Transcriptional coactivator Aly/REF; bZIP-enhancing factor BEF
Immunogen: A synthetic peptide of human Aly
Conjugate: Unconjugated
Modification: Unmodified