Annexin 6 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB0115-50, MB0115-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P08133
Host: Mouse
Reactivity: Human
Applications: WB
All Applications: WB:1:1000
Background: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Annexin 6 mAb detects endogenous levels of Annexin 6 protein.
Bioworld Molecular Weight: Predicted band size:76KDa
Observed band size:76KDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western BlotDetection of ANXA6 in T47D, MB4, CEM, MOLT-4 &Jurkat cell lysates and using ANXA6 antibody (1:1000 diluted).
Alternative Name: 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; ANXA6; Annexin VI
Immunogen: Recombinant full length Human Annexin 6.
Conjugate: Unconjugated
Modification: Unmodified