Annexin A2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90059-50, BS90059-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P07355(Human) P07356(Mouse) Q07936(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC ICC/IF FC
All Applications: WB:1:500-1:2,000
IHC:1:50-1:200
ICC:1:100-1:200
FC:1:50-1:200
Background: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Annexin A2 polyclonal antibody detects endogenous levels of Annexin A2 protein.
Bioworld Molecular Weight: 38 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Annexin A2 on different cells lysates using anti-Annexin A2 antibody at 1/500 dilution.
Positive control:
Lane 1: Hela
Lane 2: Human kidney
Lane 3: Murine testis, ICC staining Annexin A2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: PAP-IV, ANXA2, ANX2, ANX2L4, CAL1H, LPC2D, Annexin A2, Annexin II, Annexin II, heavy chain, Annexin-2, ANX 2, ANX2, ANX2L4, ANXA2, ANXA2, arylsulfatase B, CAL1H, Calpactin I heavy chain, calpactin I heavy polypeptide (p36), Calpactin I heavy polypeptide, Calpactin-1 heavy chain, chromobindin 8, Chromobindin-8, Epididymis secretory protein Li 270, HEL S 270, LIP2, Lipocortin II, LPC2, LPC2D, p36, P36 protein, PAP-IV, Placental anticoagulant protein IV, Protein I,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified