LTK (R241) Polyclonal Antibody
Catalogue Numbers:BS2267-50, BS2267-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P29376
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: IHC
All Applications: IHC: 1:50~1:200
Background: LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occuring in many non-Hodgkin’s lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bioworld Molecular Weight: ~ 92 kDa
Specificity: LTK (R241) polyclonal antibody detects endogenous levels of LTK protein.
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Leukocyte tyrosine kinase receptor; Protein tyrosine kinase 1; TYK1
Immunogen: Synthetic peptide, corresponding to amino acids 210-260 of Human LTK.
Conjugate: Unconjugated
Modification: Unmodified