Phospho-AKT2 specific-S474 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS74231-50, BS74231-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P31751
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB,1:500 - 1:2000
Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Phosphorylated
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
Immunogen: A synthetic phosphorylated peptide around S474 of human AKT2 specific.
Conjugate: Unconjugated
Modification: Phosphorylated