Phospho-Bad-S112 Polyclonal Antibody
Sizes: 50 µl, 100 µl
Catalogue Numbers: BS6336-50, BS6336-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q92934
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB,1:500 - 1:2000
Background: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Phosphorylated Antibodies
Bioworld Molecular Weight: 18kDa
Note: For research use only, not for use in diagnostic procedure.
BAD; BBC2; BCL2L8; Bad
Immunogen: A synthetic phosphorylated peptide around S112 of mouse Bad(NP_031548.1?).
Conjugate: Unconjugated
Modification: Phosphorylated