PLS3 Polyclonal Antibody
Sizes: 50 µl, 100 µl
Catalogue Numbers: BS70557-50, BS70557-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P13797
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IP
All Applications: WB,1:200 - 1:2000 | IP,1:50 - 1:100
Background: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Polyclonal Antibodies
Bioworld Molecular Weight: 71kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: PLS3; BMND18; T-plastin; plastin-3
Immunogen: Recombinant fusion protein of human PLS3(NP_005023.2).
Conjugate: Unconjugated
Modification: Unmodified