SPARC Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB66853-50, MB66853-100
Product: Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.
Swiss-Prot: P09486
Host: Mouse
Reactivity: Human
Applications: WB
All Applications: WB (1/500 - 1/1000)
Background: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recognizes endogenous levels of SPARC protein.
Bioworld Molecular Weight: ~ 40 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of SPARC expression in Hela (A) whole cell lysates., ???, ???, ???
ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SPARC. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified