U2AF1L4 Polyclonal Antibody
Sizes: 50 µl, 100 µl
Catalogue Numbers: BS8746-50, BS8746-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8WU68
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB,1:500 - 1:2000
Background: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity. Shows a preference for AGC or AGA (By similarity.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Polyclonal Antibodies
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: U2AF1L4; U2AF1-RS3; U2AF1L3; U2AF1L3V1; U2AF1RS3; U2af26
Immunogen: Recombinant fusion protein of human U2AF1L4(NP_659424.2).
Conjugate: Unconjugated
Modification: Unmodified