Recombinant Human TNFRSF11A/CD265 Protein
Size: 10UG
Catalogue Numbers: RP00458-10
Citations, Manuals and SDS Available upon request.
Description: Recombinant Human TNFRSF11A/CD265 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ile30-Pro212) of human RANK/TNFRSF11A/CD265 (Accession #Q9Y6Q6) fused with a 6×His tag at the C-terminus.
Background: This protein is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Synonyms: TNFRSF11A, CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Swiss-Prot: Q9Y6Q6
GeneID: 8792
Species: Human
Purity: > 95% by SDS-PAGE.
Research Areas: Bio-Markers & CD Antigens, TNF family
Expression System: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Endotoxin: < 1 EU/μg of the protein by LAL method.
Symbol: TNFRSF11A/CD265
Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
Keywords: Recombinant Human RANK/TNFRSF11A/CD265 Protein, TNFRSF11A, CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Research Use Only