Actin-α cardiac muscle Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21645-50, RA21645-100
Citations, Manuals and MSDS Available upon request.
Background: actin, alpha, cardiac muscle 1 (ACTC1) Homo sapiens Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC) . [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 70
Protein MW (KDa): 42
SWISS: P68032
Source: Rabbit
Research Use Only