Adipsin Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21692-50, RA21692-100
Citations, Manuals and MSDS Available upon request.
Background: catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Alternative Names: Complement factor D (EC 3.4.21.46;Adipsin;C3 convertase activator;Properdin factor D)
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1675
SWISS: P00746
Source: Rabbit
Research Use Only