ApoB (Apolipoprotein B Nano Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20455-50, RA20455-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS
Store At/In: -20°C/1 year
Recommended Dilutions: ELISA 1:10000-20000
Alternative Names: APOB; Apolipoprotein B-100; Apo B-100
Background: apolipoprotein B (APOB) Homo sapiens This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA) , resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008],
Applications: FCM; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 338
SWISS: P04114
Source: Camel
Research Use Only