Artn Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22098-50, RA22098-100
Citations, Manuals and MSDS Available upon request.
Background: artemin (ARTN) Homo sapiens This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Artemin (Enovin;Neublastin)
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 9048
SWISS: Q5T4W7
Source: Rabbit
Research Use Only