Atrophin-1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22251-50, RA22251-100
Citations, Manuals and MSDS Available upon request.
Background: atrophin 1 (ATN1) Homo sapiens Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Jul 2016],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: ATN1; D12S755E; DRPLA; Atrophin-1; Dentatorubral-pallidoluysian atrophy protein
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 1822
Protein MW (KDa): 130
SWISS: P54259
Source: Rabbit
Research Use Only