BAP1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA31266-50, RA31266-100
Citations, Manuals and MSDS Available upon request.
Background: BRCA1 associated protein 1 (BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 8314
Protein MW (KDa): 80
SWISS: Q92560
Source: Rabbit
Research Use Only