Bradykinin B1 R Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22472-50, RA22472-100
Citations, Manuals and MSDS Available upon request.
Background: bradykinin receptor B1 (BDKRB1) Homo sapiens Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 623
Protein MW (KDa): 40
SWISS: P46663
Source: Rabbit
Research Use Only