Caspase-7 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22740-50, RA22740-100
Citations, Manuals and MSDS Available upon request.
Background: caspase 7 (CASP7) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000, IF 1:50-300, IHC 1:50-300
Alternative Names: CASP7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3
Applications: WB; IHC-p; IF/ICC; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 840
Protein MW (KDa): 34
SWISS: P55210
Source: Rabbit
Research Use Only