CD177 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22959-50, RA22959-100
Citations, Manuals and MSDS Available upon request.
Background: CD177 molecule (CD177) Homo sapiens This gene encodes a glycosyl-phosphatidylinositol (GPI) -linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: CD177; NB1; PRV1; CD177 antigen; Human neutrophil alloantigen 2a; HNA-2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1; CD177
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 57126
Protein MW (KDa): 46
SWISS: Q8N6Q3
Source: Rabbit
Research Use Only