CD207 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22974-50, RA22974-100
Citations, Manuals and MSDS Available upon request.
Background: CD207 molecule (CD207) Homo sapiens The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 50489
Protein MW (KDa): 38
SWISS: Q9UJ71
Source: Rabbit
Research Use Only