CD284 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20608-50, RA20608-100
Citations, Manuals and MSDS Available upon request.
Background: toll like receptor 4 (TLR4) Homo sapiens The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: TLR4; Toll-like receptor 4; hToll; CD antigen CD284
Applications: IF/ICC; WB; IHC-p; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 7099
Protein MW (KDa): 95
SWISS: O00206
Source: Rabbit
Research Use Only