CD329 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23041-50, RA23041-100
Citations, Manuals and MSDS Available upon request.
Background: sialic acid binding Ig like lectin 8 (SIGLEC8) Homo sapiens Sialic acid-binding immunoglobulin (Ig) -like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]) .[supplied by OMIM, May 2010],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: SIGLEC8; SAF2; Sialic acid-binding Ig-like lectin 8; Siglec-8; CDw329; Sialoadhesin family member 2; SAF-2; CD329
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 27181
Protein MW (KDa): 50
SWISS: Q9NYZ4
Source: Rabbit
Research Use Only