CD89 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23112-50, RA23112-100
Citations, Manuals and MSDS Available upon request.
Background: Fc fragment of IgA receptor (FCAR) Homo sapiens This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 2204
Protein MW (KDa): 32
SWISS: P24071
Source: Rabbit
Research Use Only