Cdc42EP5 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23157-50, RA23157-100
Citations, Manuals and MSDS Available upon request.
Background: CDC42 effector protein 5 (CDC42EP5) Homo sapiens Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: CDC42EP5; BORG3; CEP5; Cdc42 effector protein 5; Binder of Rho GTPases 3
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 148170
Protein MW (KDa): 22
SWISS: Q6NZY7
Source: Rabbit
Research Use Only