Cdk5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA23194-50, RA23194-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: Cyclin-dependent kinase 5 (EC 2.7.11.22) (Cell division protein kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Background: cyclin dependent kinase 5(CDK5) Homo sapiens This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015],
Applications: WB, ELISA
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 33
Protein Molecular Weight (kDa): 33
GeneID (Human): 1020
SWISS: Q00535
Source: Rabbit
Immunogen: Synthesized peptide derived from human Cdk5. at AA range: 1-50
Category: Polyclonal
Research Use Only