CKR-1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23402-50, RA23402-100
Citations, Manuals and MSDS Available upon request.
Background: C-C motif chemokine receptor 1 (CCR1) Homo sapiens This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1) . Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: C-C chemokine receptor type 1 (C-C CKR-1;CC-CKR-1;CCR-1;CCR1;HM145;LD78 receptor;Macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;RANTES-R;CD antigen CD191)
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1230
SWISS: P32246
Source: Rabbit
Research Use Only