Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23476-50, RA23476-100
Citations, Manuals and MSDS Available upon request.
Background: cathepsin L (CTSL) Homo sapiens The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CTSL1; CTSL; Cathepsin L1; Major excreted protein; MEP
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1514
Protein MW (KDa): 30
SWISS: P07711
Source: Rabbit
Research Use Only