Cleaved-MMP-3 (F100) Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA23516-50, RA23516-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: MMP3; STMY1; Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1
Background: matrix metallopeptidase 3(MMP3) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008],
Applications: WB, ELISA
Species Cross-Reactivity: Human, Rat, Mouse,
Molecular Weight: 43
Protein Molecular Weight (kDa): 43
GeneID (Human): 4314
SWISS: P08254
Source: Rabbit
Immunogen: The antiserum was produced against synthesized peptide derived from human MMP3. AA range:81-130
Category: Polyclonal
Research Use Only