Cleaved-Notch 2 (D1733) Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA20590-50, RA20590-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: NOTCH2; Neurogenic locus notch homolog protein 2; Notch 2; hN2
Background: notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle
Applications: IF/ICC, WB, IHC-p, ELISA
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 100+130
Protein Molecular Weight (kDa): 100+130
GeneID (Human): 4853
SWISS: Q04721
Source: Rabbit
Immunogen: The antiserum was produced against synthesized peptide derived from human Notch 2. AA range:1684-1733
Category: Polyclonal
Research Use Only