Cleaved-Notch 2 (D1733) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20590-50, RA20590-100
Citations, Manuals and MSDS Available upon request.
Background: notch 2 (NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: NOTCH2; Neurogenic locus notch homolog protein 2; Notch 2; hN2
Applications: IF/ICC; WB; IHC-p; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 4853
Protein MW (KDa): 100+130
SWISS: Q04721
Source: Rabbit
Research Use Only