Cleaved-PARP-1 (G215) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20591-50, RA20591-100
Citations, Manuals and MSDS Available upon request.
Background: poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 142
Protein MW (KDa): 89
SWISS: P09874
Source: Rabbit
Research Use Only