CPE Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23735-50, RA23735-100
Citations, Manuals and MSDS Available upon request.
Background: carboxypeptidase E (CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: CPE; Carboxypeptidase E; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 1363
Protein MW (KDa): 53
SWISS: P16870
Source: Rabbit
Research Use Only