CRLF2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA31827-50, RA31827-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background: cytokine receptor-like factor 2(CRLF2) Homo sapiens This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
Applications: WB, ELISA
Species Cross-Reactivity: Human, Rat, Mouse
Molecular Weight: 40
Protein Molecular Weight (kDa): 40
GeneID (Human): 64109
SWISS: Q9HC73
Source: Rabbit
Immunogen: Synthesized peptide derived from part region of human protein
Category: Polyclonal
Research Use Only