CRSP150 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA23817-50, RA23817-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: MED14; ARC150; CRSP2; CXorf4; DRIP150; EXLM1; RGR1; TRAP170; Mediator of RNA polymerase II transcription subunit 14; Activator-recruited cofactor 150 kDa component; ARC150; Cofactor required for Sp1 transcriptional activation subunit 2; CRS
Background: mediator complex subunit 14(MED14) Homo sapiens The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008],
Applications: IHC-p, IF/ICC, ELISA
Species Cross-Reactivity: Human, Mouse
GeneID (Human): 9282
SWISS: O60244
Source: Rabbit
Immunogen: The antiserum was produced against synthesized peptide derived from human MED14. AA range:701-750
Category: Polyclonal
Research Use Only