Cyclin E2 (phospho Thr392) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23941-50, RA23941-100
Citations, Manuals and MSDS Available upon request.
Background: cyclin E2 (CCNE2) Homo sapiens The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CCNE2; G1/S-specific cyclin-E2
Applications: IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 9134
SWISS: O96020
Source: Rabbit
Research Use Only