Cyclin T2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA23949-50, RA23949-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: IHC-p 1:50-200, WB 1:500-2000
Purification Technology:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Alternative Names: Cyclin-T2 (CycT2)
Background: cyclin T2(CCNT2) Homo sapiens The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010],
Applications: IHC-p, IF (paraffin section), WB
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 73
Protein Molecular Weight (kDa): 73
GeneID (Human): 905
SWISS: O60583
Source: Rabbit
Immunogen: Synthesized peptide derived from human Cyclin T2
Category: Polyclonal
Research Use Only