CYP11B1/2 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA23959-50, RA23959-100
Citations, Manuals and MSDS Available upon request.
Background: cytochrome P450 family 11 subfamily B member 1 (CYP11B1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: CYP11B1; S11BH; Cytochrome P450 11B1; mitochondrial; CYPXIB1; Cytochrome P-450c11; Cytochrome P450C11; Steroid 11-beta-hydroxylase; CYP11B2; Cytochrome P450 11B2, mitochondrial; Aldosterone synthase; ALDOS; Aldosterone-synthesizing enzyme;
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1584/1585
Protein MW (KDa): 57
SWISS: P15538/P19099
Source: Rabbit
Research Use Only