CYP2C8 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA23983-50, RA23983-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: IHC-p: 1/100 - 1/300. IF:1:50-200 ELISA: 1/20000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: CYP2C8; Cytochrome P450 2C8; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase
Background: cytochrome P450 family 2 subfamily C member 8(CYP2C8) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
Applications: IHC-p, IF/ICC, ELISA
Species Cross-Reactivity: Human, Rat, Mouse,
GeneID (Human): 1558
SWISS: P10632
Source: Rabbit
Immunogen: The antiserum was produced against synthesized peptide derived from human CYP2C8. AA range:241-290
Category: Polyclonal
Research Use Only