DAAM1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24070-50, RA24070-100
Citations, Manuals and MSDS Available upon request.
Background: dishevelled associated activator of morphogenesis 1 (DAAM1) Homo sapiens Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl) -Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000
Alternative Names: Disheveled-associated activator of morphogenesis 1
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 23002
Protein MW (KDa): 123
SWISS: Q9Y4D1
Source: Rabbit
Research Use Only