DCTN4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA31942-50, RA31942-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background: function:Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,similarity:Belongs to the dynactin subunit 4 family.,subcellular location:Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution, suggesting that this polypeptide may be targeted to the nucleus at very high expression levels.,subunit:Member of the pointed-end complex of the dynactin shoulder complex which contains DCTN4, DCTN5 and DCTN6 subunits and ACTR10 (By similarity). Binds directly to the ACTR1A subunit of dynactin.,
Applications: WB, ELISA
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 50
Protein Molecular Weight (kDa): 50
GeneID (Human): 51164
SWISS: Q9UJW0
Source: Rabbit
Immunogen: Synthesized peptide derived from part region of human protein
Category: Polyclonal
Research Use Only