DDR1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA11086-50, RA11086-100
Citations, Manuals and MSDS Available upon request.
Condition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Store at: -20°C/1 year
Recommended Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification Technology: Affinity purification
Alternative Names: DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2,
Background: discoidin domain receptor tyrosine kinase 1 (DDR1) Homo sapiens Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],
Applications: WB, ELISA
Species Cross-Reactivity: Human
GeneID (Human): 780
SWISS: Q08345
Source: Mouse
Immunogen: Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.
Category: Monoclonal
Research Use Only