Defensin α4 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24166-50, RA24166-100
Citations, Manuals and MSDS Available upon request.
Background: defensin alpha 4 (DEFA4) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: DEFA4; DEF4; Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1669
SWISS: P12838
Source: Rabbit
Research Use Only