DMA Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA32014-50, RA32014-100
Citations, Manuals and MSDS Available upon request.
Background: major histocompatibility complex, class II, DM alpha (HLA-DMA) Homo sapiens HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
Protein MW (KDa): 28
SWISS: P28067
Source: Rabbit
Research Use Only