DMGDH Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24238-50, RA24238-100
Citations, Manuals and MSDS Available upon request.
Background: dimethylglycine dehydrogenase (DMGDH) Homo sapiens This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 29958
Protein MW (KDa): 97
SWISS: Q9UI17
Source: Rabbit
Research Use Only