DNA pol β (Acetyl Lys72) Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24248-50, RA24248-100
Citations, Manuals and MSDS Available upon request.
Background: catalytic activity:Deoxynucleoside triphosphate + DNA (n) = diphosphate + DNA (n+1) .,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000
Alternative Names: DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 5423
Protein MW (KDa): 38
SWISS: P06746
Source: Rabbit
Research Use Only