DNMT1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA20983-50, RA20983-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background: DNA methyltransferase 1(DNMT1) Homo sapiens This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Applications: WB, ELISA
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 177
Protein Molecular Weight (kDa): 177
GeneID (Human): 1786
SWISS: P26358
Source: Rabbit
Immunogen: Synthesized peptide derived from part region of human protein
Category: Polyclonal
Research Use Only