DOCK 2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA24284-50, RA24284-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Background: dedicator of cytokinesis 2(DOCK2) Homo sapiens The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],
Applications: IHC-p, IF (paraffin section), ELISA
Species Cross-Reactivity: Human, Mouse, Rat
GeneID (Human): 1794
SWISS: Q92608
Source: Rabbit
Immunogen: Synthesized peptide derived from the Internal region of human DOCK 2.
Category: Polyclonal
Research Use Only