DR4 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24322-50, RA24322-100
Citations, Manuals and MSDS Available upon request.
Background: TNF receptor superfamily member 10a (TNFRSF10A) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: TNFRSF10A; APO2; DR4; TRAILR1; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD antigen CD261
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Monkey
GeneID (Human): 8797
Protein MW (KDa): 50
SWISS: O00220
Source: Rabbit
Research Use Only