Dynein IC1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24369-50, RA24369-100
Citations, Manuals and MSDS Available upon request.
Background: dynein axonemal intermediate chain 1 (DNAI1) Homo sapiens This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: DNAI1; Dynein intermediate chain 1; axonemal; Axonemal dynein intermediate chain 1
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 27019
Protein MW (KDa): 79
SWISS: Q9UI46
Source: Rabbit
Research Use Only